PandaDoc and Docusign are an even split for document signing tools that integrate with CRM software. Adobe Acrobat Sign is also framed for larger organizations already using Adobe.
Sales proposals + contracts + signatures in one workflow
Adobe Acrobat Sign
Salesforce, Microsoft Dynamics 365, HubSpot and others
Enterprise document workflows and compliance
Dropbox Sign
Salesforce, HubSpot, Microsoft Dynamics
Simpler e-signing with strong CRM connectivity
My recommendation
If you're using Salesforce: start with DocuSign or PandaDoc. DocuSign can create/send agreements directly from Salesforce, track status, and store agreements on the underlying Account or Opportunity.
If you're using HubSpot: I'd lean toward PandaDoc if you need proposals/quotes as well as signatures. PandaDoc supports two-way CRM data synchronization, while DocuSign can create, send, manage, and track envelopes directly from HubSpot records.
If you're using Microsoft Dynamics 365:Adobe Acrobat Sign is particularly compelling. It operates inside Dynamics, can merge CRM data into agreements, push signer data back into Dynamics, and attach signed documents/audit trails to customer records.
If you want something relatively straightforward: Dropbox Sign supports native Salesforce integration and can also prepare/send documents directly from Dynamics 365, with completed forms saved back to Dynamics.
If you tell me which CRM you use (Salesforce, HubSpot, Dynamics, Zoho, Pipedrive, etc.), I can narrow this to the best 2–3 options, including pricing, integration depth, and setup requirements.
Adobe Acrobat Sign — Best if you are embedded in the Microsoft ecosystem or need robust PDF-centric workflows. It offers plug-and-play integrations with Microsoft Dynamics 365 to auto-populate contract fields from CRM data and push signed files back to the client profile.
Conga Sign — Best for Salesforce-heavy environments. It pairs with Conga Composer to automate document generation and signature collection without ever leaving your Salesforce ecosystem.
GetAccept — Best for sales engagement. It goes beyond simple signatures by adding digital sales rooms, video intros, and active tracking directly inside your CRM pipeline.
If you let me know which CRM you are currently using (e.g., Salesforce, HubSpot, Zoho, Microsoft Dynamics) and whether you need quote generation or just basic signing , I can recommend the most seamless fit.
When looking for an e-signature platform with robust, native CRM integration (allowing you to generate, send, track, and manage signatures directly inside your CRM records), several top-tier platforms stand out depending on your primary CRM and workflow complexity:[](https://www.pandadoc.com/blog/best-esignature-tool-for-sales/)
DocuSign : The gold standard for enterprise security and compliance. It features deeply embedded, native integrations with major CRMs like Salesforce and HubSpot (as well as Microsoft Dynamics). Users can trigger envelopes, map CRM data fields directly onto agreements, and track signing statuses without leaving the CRM environment.[](https://albato.com/blog/publications/best-e-signature-software)
PandaDoc : Ideal for sales teams that need an all-in-one document workflow. Rather than just signing static PDFs, PandaDoc combines drag-and-drop proposal/quote creation with native e-signatures. It offers deep, bi-directional native integrations with HubSpot, Salesforce, Pipedrive, and Close, automatically syncing deal stages and contact data when documents are viewed or signed.[](https://www.pandadoc.com/blog/best-esignature-tool-for-sales/)
Adobe Acrobat Sign : Highly robust for enterprise environments heavily invested in the Microsoft or Salesforce ecosystems. It allows seamless document routing, tracking, and legally binding sign-offs directly from standard CRM interfaces with heavy customization and enterprise-grade audit trails.
Conga Sign : Specifically built for complex, sales-led operations natively within the Salesforce ecosystem. Conga merges document generation (Conga Composer) with native e-signatures (Conga Sign), tying quoting, contract generation, and final sign-offs directly to Salesforce opportunity objects.
To help narrow down the best fit, could you share:
Which CRM you are currently using (e.g., Salesforce, HubSpot, Microsoft Dynamics)?
Whether you just need simple e-signatures or an end-to-end proposal and quoting workflow?
If you're looking for an e-signature platform with native CRM integration, I'd start with DocuSign, PandaDoc, and Adobe Acrobat Sign. The best choice depends on your CRM and whether you primarily need signature collection or a more complete sales-document workflow.
My top recommendations
1. DocuSign
(Best all-around choice)
A strong starting point for organizations that need established e-signature workflows connected to their CRM. Salesforce offers a native integration, and HubSpot supports creating, sending, and tracking DocuSign envelopes directly on CRM records.
Best for: Sales teams, legal agreements, and organizations that prioritize signature workflows.
Offers native CRM integrations with Salesforce, HubSpot, Pipedrive, Microsoft Dynamics, and other CRM systems. Its two-way sync capabilities can keep CRM information and document activity aligned, depending on the integration and plan.
Best for: Teams that create proposals, quotes, and contracts and want document generation and e-signatures in one workflow.
Explore:
3. Adobe Acrobat Sign
A particularly good option for Microsoft Dynamics 365 environments. Its integration supports sending agreements within Dynamics, populating documents with CRM data, tracking signature status, and returning signed documents and signer data to CRM records.
Best for: Enterprises already using Microsoft business applications, PDF workflows, and formal document processes.
Explore:
Quick comparison
Capability
DocuSign
PandaDoc
Adobe Acrobat Sign
Salesforce
Yes
Yes
Yes
HubSpot
Yes
Yes
Check your required workflow
Microsoft Dynamics 365
Check specific connector
Yes
Yes
Proposal and quote creation
Good
Excellent
Good
CRM data mapping and sync
Integration-dependent
Strong sales-document focus
Strong for Dynamics
Best fit
E-signatures at scale
Sales document automation
Microsoft-centric enterprises
CRM features, sync capabilities, and licensing vary by integration and subscription. Confirm the exact edition and features before purchasing.
My recommendation
Choose DocuSign if electronic signatures are your primary requirement and you want a widely used platform.
Choose PandaDoc if you want to generate proposals and contracts from CRM data, then track them through signing.
Choose Adobe Acrobat Sign if your organization relies heavily on Microsoft Dynamics 365 and the Microsoft ecosystem.
One question will help me narrow this to the best fit: Which CRM are you using?
1. Your CRM platform
Salesforce
HubSpot
Microsoft Dynamics 365
Pipedrive
Zoho CRM
Other
2. Your main requirement
Basic e-signatures
Document creation, CRM data mapping, and signatures