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UNP develops synthetic macrocyclic peptides that offer antibody-like precision with oral small-molecule delivery, enabling targeting of intracellular and extracellular pathways. It operates a scalable, repeatable platform that continuously designs, synthesizes, and tests macrocycles in a digital-physical loop to rapidly improve potency, selectivity, and permeability. Through an internal portfolio and top-tier partnerships—including licensing and research collaborations for cardiovascular diseases and other hard-to-drug targets—UNP aims to address unmet medical needs from its Santa Cruz, California hub.
AI named Unnatural Products in March 2026.