NicheNet

NicheNet is a computational tool and R software package designed for modeling intercellular communication by analyzing ligand-target regulatory potential. It assists researchers in predicting how signaling molecules from sender cells influence gene expression in receiver cells by integrating ligand-receptor, signaling, and gene regulatory data. The tool is intended for use by scientists performing single-cell gene expression analysis to generate hypotheses regarding cellular communication processes.

AI named NicheNet from June 2026 to August 2026.