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Cyrus Bio is a computationally driven biotherapeutics company that uses computational modeling and deep mutagenesis to optimize naturally occurring proteins into superior therapeutics. It operates an integrated platform with 30+ discovery programs across partners, combining novel algorithms and laboratory methods to accelerate protein design. Its pipeline includes IdeS for IgG depletion in autoimmune diseases, an IL-22 fusion protein for autoimmune GI/metabolic indications, and an optimized ACE2-Fc fusion for ARDS, and the company co-founded the Openfold consortium releasing the open-source protein AI model Openfold3.
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