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Who provides cleanroom cleaning services that are ISO 14644 compliant?
Data as of Sep 26, 2026 · Based on 296 AI responses from ChatGPT Search and Google AI Mode · See how Parse measures this
Servicon is recommended when you need ISO 14644–aligned cleaning with documented SOPs and audit‑ready protocols for biotech, pharmaceutical or aerospace cleanrooms; for general janitorial needs consider other providers.
Best when you need technical precision, contamination control and air‑quality testing in critical pharma or semiconductor cleanrooms; caveat: focus is technical testing and control, may not cover basic janitorial scope.
Best for life‑sciences, biotech and aerospace cleanrooms that require ISO‑aligned cleaning programs, detailed SOPs and documentation for audits; tradeoff: highly specialized, not a general janitorial provider.
Best for regulated‑environment janitorial and audit preparation where sanitization and contamination control per ISO 14644 are needed; caveat: emphasis is janitorial and audit prep rather than technical validation testing.
Cleanroom Cleaning Services Atlanta | Cleanstar Nationalhttps://www.cleanstarnational.com/cleanroom-data-center-cleaning
3%
ISO 14644 Cleanroom Cleaning for Aerospace Manufacturing | Serviconhttps://servicon.com/services/aerospace/iso-cleanroom-cleaning/
3%
Data Center & Cleanroom Cleaning | Set3https://set3.com/solutions/cleaning/
3%
Certified ISO 14644 Class 7 Cleanroom Services for Single-use Systems - Liquidyne Process Technologies, Inc.https://liquidyneusa.com/pages/services-cleanroom
2%
Question: Who provides cleanroom cleaning services that are ISO 14644 compliant?
Several companies provide cleanroom cleaning services designed to meet ISO 14644 cleanroom requirements. The right provider depends on your cleanroom class (ISO 5–8, etc.), industry (pharma, biotech, semiconductor, aerospace, healthcare, data centers), and whether you need routine cleaning, decontamination, validation support, or certification testing.
Some providers include:
Cleanroom Facility Solutions — Provides cleanroom cleaning, GMP decontamination, and critical-environment services with programs aligned to ISO 14644 requirements for regulated industries.
Astro Pak — Offers precision cleaning and cleanroom services, including ISO 14644-1 certified cleanroom facilities and cleanliness verification support for industries such as aerospace, pharmaceutical, biotechnology, and semiconductor.
CRM CleanRooms — Provides cleanroom cleaning, testing, and certification services with ISO 14644-1 compliance support.
Continental Cleaning — Specializes in classified-environment cleaning and certification, including ISO 14644-1 cleanroom programs.
SET3 — Provides critical-environment cleaning, decontamination, air-quality testing, and ISO-related compliance services for cleanrooms and other controlled environments.
Micro Clean Services — Provides cleanroom decontamination cleaning using ISO 14644-based practices and cleanroom protocols.
GL Technologies — Supports cleanroom cleaning, sterilization, testing, and ISO 14644-related compliance needs, particularly for biopharma and medical device environments.
When selecting a vendor, ask for:
ISO 14644-1 classification experience matching your room class
Written SOPs for cleanroom cleaning methods
Technician training records (cleanroom gowning, contamination control)
HEPA-filtered vacuum and cleanroom-approved materials
Particle-count testing and documentation (if required)
Experience with your regulatory environment (FDA GMP, USP <797>/<800>, semiconductor, aerospace, etc.)
If you share your location, ISO class (e.g., ISO 5, 6, 7, 8), and industry, I can narrow this to suitable providers.
Several specialized facilities and contamination control providers offer cleanroom cleaning services designed to meet ISO 14644 standards (covering air cleanliness and particulate control classifications from ISO Class 1 through ISO Class 9).
Prominent providers delivering ISO 14644-compliant cleanroom cleaning and decontamination include:
SET3 — Specializes in ISO 14644, FDA, and IEST-compliant cleaning, surface decontamination, and maintenance for sensitive cleanrooms and semiconductor/aerospace environments across various classifications.
Servicon — Provides tailored, high-compliance cleanroom cleaning for life sciences, aerospace, and high-tech manufacturing, ensuring strict adherence to ISO 14644 protocols, trained micro-cleaners, and audit documentation.
Controlled Contamination Services (CCS) — Offers nationwide controlled environment micro-cleaning, decontamination, and regulatory compliance support ranging from ISO Class 3 (Grade A) to ISO Class 9 (Grade D).
Cleanroom Facility Services — Delivers nationwide cleaning, testing, and ISO 14644-1/-2 certification services for pharmaceutical, medical device, and semiconductor manufacturing cleanrooms.
Vericlean — Focuses on critical environment and GMP-compliant cleanroom cleaning with verifiable audit trails and validation testing (such as ATP testing) primarily serving high-tech and biotech hubs.
To help narrow down the right provider, could you share:
What ISO cleanroom class (e.g., ISO Class 5, ISO Class 7) your facility operates?
Your geographic location or facility footprint?
Whether you need routine ongoing maintenance or a one-time/initial construction decontamination?
Uniserve Facilities Services - 2363 S Atlantic Blvd, Commerce, CA 90040, United States
Cleanroom Facility Services - 18100 Von Karman Ave #850, Irvine, CA 92612, United States
Advanced Cleanroom Microclean (ACM) - 3250 S Susan St # A, Santa Ana, CA 92704, United States
Controlled Contamination Services - 11526 Sorrento Valley Rd Ste G, San Diego, CA 92121, United States
Astro Pak - 12201 Pangborn Ave, Downey, CA 90241, United States
Quality Precision Cleaning - 5795 Martin Rd, Irwindale, CA 91706, United States
Uniserve Facilities Services Corporation - 550 S Hope St, Los Angeles, CA 90071
Prudential Cleanroom Services - 6948 Bandini Blvd, Commerce, CA 90040, United States
UG2 Facility Services - 700 Flower St #2526, Los Angeles, CA 90017, United States
iNX Commercial Cleaning Solutions - 1110 N Virgil Ave PMB 90425, Los Angeles, CA 90029, United States
Hew Tek Precision Cleaning - 582 Porter Way, Placentia, CA 92870, United States
Quality Precission Cleaning - 1803 Business Center Dr, Duarte, CA 91010
If you’re looking in Southern California, several companies advertise cleanroom cleaning programs aligned with ISO 14644. One important distinction: ISO 14644 is primarily a cleanroom classification/testing standard, so I’d ask vendors to document exactly how their cleaning procedures maintain the required particle-class conditions, rather than simply accepting “ISO compliant” as a marketing claim.
Providers to consider
Uniserve Facilities Services — Commerce/Los Angeles area. Their cleanroom program is described as ISO 14644-1-aligned, covering Classes 5–9, with GxP-oriented environmental services and documented service records.
Cleanroom Facility Services — Irvine. Offers cleanroom cleaning/disinfection along with ISO 14644-1/2 testing and certification, HEPA services, environmental monitoring, and GMP-oriented programs.
Advanced Cleanroom Microclean (ACM) — Santa Ana. Provides cleanroom cleaning as well as certification/testing, including HEPA integrity, airflow, pressure differential and particle-count testing.
Controlled Contamination Services — San Diego, serving the broader region. Focuses specifically on contamination-control cleaning and states that its programs support FDA, USP, ISO 14644 and Annex 1 requirements.
SeaCrest Services California — explicitly advertises cleanroom/laboratory cleaning that is ISO 14644 compliant, including customized viable/non-viable environmental cleaning programs, and lists Los Angeles, Orange County, Riverside and San Diego among its service areas.
For precision cleaning of components rather than janitorial cleaning of the room itself, Astro Pak in Downey is another relevant option. Its California facility has ISO 14644-1-certified Class 5/6 cleanrooms and provides precision cleaning, testing and packaging.
What I'd ask each vendor
Before selecting one, ask for:
Which ISO 14644 standard(s) their cleaning SOPs are based on—e.g. ISO 14644-1 classification and ISO 14644-2 monitoring.
The cleanroom class they routinely service (ISO 5, 6, 7, 8, or 9).
Whether technicians are trained specifically in cleanroom cleaning and contamination control, rather than general janitorial work.
HEPA-filtered vacuum/equipment and approved cleanroom wipes, mops and disinfectants.
Whether they provide particle-count testing after cleaning and documented reports.
Experience with your applicable GMP, FDA, USP <797>/<800>, semiconductor, aerospace, medical-device, or other requirements.
Whether they can provide their SOP, training records, cleaning validation/qualification documentation and certificates for an audit.
If you tell me your city, cleanroom ISO class (e.g. ISO 7), industry (pharma, medical device, semiconductor, aerospace, etc.), and approximate square footage, I can narrow this to the most relevant vendors and compare their capabilities.
Several reputable nationwide and regional facility service providers specialize in cleanroom maintenance and decontamination that comply with ISO 14644 standards.
Controlled Contamination Services (CCS) — Specializes in critical facility services and regulated environments (biotech, pharmaceutical, medical device, aerospace, and semiconductor), offering ISO-compliant cleanroom cleaning and bio-decontamination.
Servicon — Provides specialized, highly trained cleaning teams for aerospace, healthcare, and high-tech manufacturing, specifically structured around maintaining ISO 14644 compliance.
SET3 — Focuses on data center and cleanroom environment maintenance, adhering directly to ISO 14644, ASHRAE, and IEST standards for subfloor, overhead, and critical equipment cleaning.
Quantus — Specializes heavily in cleanroom certification, testing, and validation ensuring strict alignment with ISO 14644 parameters (such as particle counts and airflow velocity).
If you'd like to narrow this down, please let me know:
What ISO class level your cleanroom is (e.g., ISO 5, ISO 7, ISO 8)
Your industry (pharmaceutical, aerospace, electronics, etc.)
Your geographic location or facility coverage area
Cleanetics - 6850 N Haggerty Rd, Canton Township, MI 48187, United States
CleanSpace - 2424 Wolcott St, Ferndale, MI 48220, United States
Sterile Science - 1033 Graceland Ave, Des Plaines, IL 60016, United States
Clean Air Technology Inc. - Custom Cleanrooms Manufacturer, Design/Build/Install - 41105 Capital, Canton Township, MI 48187, United States
Clean Air Testing Inc - 37709 Schoolcraft, Livonia, MI 48150, United States
Clean Air Testing Inc - 28935 Lancaster St, Livonia, MI 48154, United States
Lake Michigan Cleaning Service - 200 E Big Beaver Rd, Troy, MI 48083, United States
Elite Cleanroom Services - 548 S Court St, Lapeer, MI 48446, United States
Cleanetics - 814 5th St, West Elizabeth, PA 15088, United States
Yes. If you're looking in Southeast Michigan/Metro Detroit, I found several providers that specifically work with cleanrooms and ISO 14644 requirements.
Cleanetics — Canton, MI
One of the strongest local options. Cleanetics provides micro-cleaning, cleanroom maintenance, certification, environmental monitoring, and contamination-control services. Its maintenance programs specifically reference ISO 14644-1, including clean-down procedures, wall cleaning, HEPA/FFU maintenance, particle counts, and certification.
City Wide Facility Solutions — Southeast Michigan
Offers dedicated cleanroom and laboratory cleaning and says its crews implement and maintain ISO 14644 protocols, covering ISO Classes 5–9. Services include gown-room cleaning, ESD floor care, SOP development, monitoring documentation, and H₂O₂ fogging.
Paragon International — Detroit area
Provides specialized cleanroom cleaning with trained technicians, gowning procedures, contamination-control methods, and services for pharmaceutical and biotechnology environments.
CleanShield / CleanSpace — Ferndale, MI
A specialized clean-environment provider supporting pharmaceutical, biotech, cell/gene therapy, and other controlled environments. Their Michigan operation works with facilities designed around ISO cleanroom classifications.
Sterile Science — serves the Midwest/nationally
Specializes in cleanroom cleaning, decontamination and sterilization, including GMP environments. This is worth considering if you need a highly documented, compliance-oriented cleaning program rather than ordinary janitorial service.
My shortlist
For a facility in the Westland/Canton/Livonia area, I'd start with Cleanetics and City Wide. Cleanetics is particularly attractive if you need both cleaning and ISO 14644 testing/certification, while City Wide appears more focused on recurring operational cleaning.
One important distinction: ISO 14644 is primarily a cleanroom performance/classification standard, not a certification that a cleaning company itself holds. When soliciting bids, I'd ask the contractor to demonstrate that its cleaning SOPs, personnel training, equipment, chemicals, gowning, documentation, and cleaning frequencies are appropriate for your specific ISO class—and ask how they verify that cleaning doesn't compromise your particle/microbial limits.
If you tell me your ISO class (e.g., ISO 5, 6, 7, or 8), industry, and approximate cleanroom square footage, I can narrow this to the best 3–5 providers and compare their services and contact information.
Several specialized facility care and contamination control providers offer cleanroom cleaning services designed to meet ISO 14644 compliance standards (covering cleanroom classification, biocontamination control, and operational testing).
Prominent national and regional providers specializing in these controlled environments include:
SET3 – Specializes in ISO 14644, FDA, and IEST-compliant cleaning, decontamination, and environmental testing for ISO 1–9 cleanrooms, serving sectors from semiconductor manufacturing to sterile production zones.
Servicon – Focuses on complex, high-regulated facilities like life sciences and biotech laboratories, providing tailored cleanroom maintenance and disinfection that meets strict regulatory frameworks.
Controlled Contamination Services (CCS) – Delivers specialized GMP-compliant and ISO-aligned contamination control, routine micro-cleaning, and environmental hygiene services for life sciences, high-tech, aerospace, and pharmaceutical facilities.
Advanced Cleanroom Microclean (ACM) – Offers specialized janitorial and cleaning protocols executed by certified cleanroom technicians tailored to manage particle counts and adhere to strict cleanroom classifications.[1]
If you'd like to narrow this down, please let me know:
What ISO cleanroom class (e.g., ISO Class 5, ISO Class 7) your facility operates
Your industry (pharmaceutical, semiconductor, aerospace, medical device)
Your location or region
I can help you pinpoint a provider or outline specific protocols required for your classification.
Several specialized facility maintenance and contamination control providers offer cleanroom cleaning services designed to meet ISO 14644 compliance standards (covering air and surface particulate cleanliness classifications from ISO Class 1 through 9).
Prominent nationwide and regional providers offering these services include:
Controlled Contamination Services (CCS) : Specializes in micro-cleaning services ranging from ISO Class 3 (Grade A) through ISO Class 9 (Grade D), alongside protocol development, cleanroom audits, and environmental monitoring.
Servicon : Provides customized, high-level complex facility care and contamination cleaning tailored to life sciences, aerospace, and high-tech manufacturing industries requiring strict ISO 14644 compliance.
SET3 Cleanroom Environment Experts : Focuses on ISO 14644, FDA 503, and IEST RP compliant surface decontamination, routine or emergency cleaning, and certification supporting ISO Class 1–9 environments.
If you would like to narrow this down, let me know:
Your cleanroom's ISO class (e.g., ISO Class 5, 7)
Your industry (e.g., pharmaceutical, aerospace, semiconductor)
Your geographic location or facility footprint
I can help identify which provider specializes best in your region and sector.
Uni Clean - 8 Hixon Pl, Maplewood, NJ 07040, United States
CleanTech Systems, Inc. - 153 Andover St #115, Danvers, MA 01923, United States
United Contamination Control - 241 Zimmerman Ln, Langhorne, PA 19047, United States
AAK CLEANROOMS & SCIF's LLC - 1-95 Beach 96th St, Rockaway Beach, NY 11693, United States
G And A Cleaning - Delair, NJ 08110
TFE CLEANROOMS LLC - 1-95 Beach 96th St, Rockaway Beach, NY 11693, United States
Yes. If you’re looking for specialized cleanroom cleaning—not ordinary commercial janitorial service—there are several providers that explicitly work to ISO 14644 requirements. Since you appear to be in the NJ/NY area, I’d start with these:
SterileNetics — Lebanon, NJ. Specializes in cleanroom and controlled-environment cleaning, decontamination, contamination control, and deep “superclean”/shutdown services.
Controlled Contamination Services - New Jersey — Marlton, NJ. Focuses specifically on critical/controlled environments and provides cleaning programs spanning ISO-classified environments, with GMP/ISO-oriented documentation and protocols.
Bravos's Maintenance Solutions — Hicksville, NY, serving NJ and nationwide. Provides cleanroom/GMP facility cleaning, gown-qualified personnel, documented procedures, and audit-ready records. Their service area explicitly includes New Jersey.
Uni Clean — Maplewood, NJ. Offers specialized cleanroom cleaning by trained technicians, with service frequencies tailored to the customer's requirements.
CleanTech Systems, Inc. — New England-based provider specializing in ISO-classified cleanrooms, GMP-trained technicians, disinfection/decontamination, documentation, and inspection procedures.
United Contamination Control — Langhorne, PA. A contamination-control/precision-cleaning company with experience in high-purity environments and on-site services.
Able Facility Solutions — serves the NJ/NY/Philadelphia region and explicitly describes its cleanroom work as ISO 14644-aligned, including cleanroom-appropriate tools, gowning, HEPA filtration, documented procedures, and contamination control.
Continental Cleaning — a nationwide provider that specifically advertises ISO 14644-1 classified cleaning and certification, covering ISO Classes 1–9.
One important distinction
I'd ask vendors whether they mean “cleaning performed according to ISO 14644 protocols” versus actually maintaining/validating the room's ISO classification.
ISO 14644 primarily establishes requirements for cleanroom classification and contamination control; a cleaning contractor shouldn't automatically be assumed to be an ISO certification body. For a regulated facility, I'd want the vendor to provide:
Written SOPs specific to your ISO class
Gowning and personnel-training records
HEPA/ULPA vacuum and non-shedding materials
Approved cleaning/disinfectant list
Cleaning logs and traceability
Particle-count or environmental-monitoring documentation where applicable
Experience with your specific ISO class (e.g., ISO 5, 6, 7, or 8)
GMP/cGMP experience if you're pharmaceutical, biotech, or medical-device
Clear distinction between cleaning and ISO 14644 testing/certification
If you tell me your location, ISO class (e.g. ISO 5/7/8), industry, and approximate square footage, I can narrow this down to the 5 best-qualified providers and compare their capabilities, service area, and contact information.
CLEANROOM CONSULTANTS & CERTIFICATIONS - 812 San Antonio St, Austin, TX 78701, United States
Yes. If you mean specialized cleanroom cleaning providers whose procedures are designed around ISO 14644 contamination-control requirements, there are several credible options in the U.S. Since you appear to be in the Houston area, I’d start with these:
Cleanroom Facility Services — Nationwide provider focused specifically on cleanroom cleaning, GMP decontamination, certification/testing, and controlled environments. It states that its cleaning programs meet FDA, USP, and ISO 14644 requirements and serves Houston.
Controlled Contamination Services — Specializes in contamination-control cleaning from ISO 3/Grade A through ISO 9/Grade D, with programs aligned to ISO 14644, FDA, USP, Annex 1 and other requirements.
Sealco — Houston-area specialist in critical-environment and cleanroom cleaning, particularly suitable for technically sensitive facilities.
Total Cleaning Solutions — Houston-based commercial provider that offers cleanroom cleaning/management and environmental-control support.
Micro Clean Services (MCS) — Nationwide cleanroom and data-center cleaning company. It specifically says its decontamination cleaning is performed in accordance with ISO 14644 and cleanroom protocols.
One important distinction
ISO 14644 isn't simply a "cleaning certification." It establishes requirements for cleanroom classification and contamination control. So when evaluating a cleaning contractor, I'd ask for:
Their cleaning SOPs mapped to your ISO 14644 classification
Technician training/qualification records
Approved cleaning agents, wipes, mops and HEPA equipment
Gowning and material-transfer procedures
Particle-control/contamination-control procedures
Cleaning validation or environmental-monitoring support
Documentation suitable for GMP/FDA audits, if applicable
References from facilities with the same ISO class and industry as yours
If this is for a Houston-area facility, I can narrow this down to 5–10 providers that actually service Houston, compare their ISO/GMP credentials, industries served, and contact information, and identify which ones are best for ISO 5, ISO 7, ISO 8, pharmaceutical, semiconductor, aerospace, or medical cleanrooms.
Several specialized national and regional providers offer cleanroom cleaning, decontamination, and validation services compliant with ISO 14644 standards (covering ISO Class 1 through 9).
SET3 Cleanroom Environment Experts - Specializes in ISO 14644, FDA 503, and IEST RP compliant cleaning, surface decontamination, and routine or emergency maintenance for semiconductor, aerospace, and sterile production environments.
Advanced Cleanroom Microcleaning (ACM) - Provides comprehensive ISO 14644-4 construction cleaning, validated GMP cleaning, and annual certification/testing per ISO 14644-2 for pharmaceutical, medical device, and tech industries.
Servicon Life Sciences - Offers specialized, audit-ready cleanroom cleaning and compliance expertise tailored for high-tech, healthcare, and life science facilities operating under strict regulatory frameworks.
If you'd like, let me know:
What ISO Class your cleanroom is (1 through 9)
Your industry (pharmaceutical, aerospace, semiconductor, etc.)
Whether you need routine maintenance or a one-time/construction deep clean
I can help narrow down which provider fits your exact needs.
City Wide Facility Solutions – West Los Angeles — advertises laboratory and cleanroom cleaning with experience implementing ISO 14644 and BSL protocols.
SET3 / Sterile Environment Technologies — Nationwide critical-environment cleaning and decontamination provider with 30+ years in the field; offers ISO 14644-oriented cleanroom cleaning, testing and consulting.
CRM CleanRooms — Provides cleaning, testing and certification, with micro-cleaning/disinfection programs and ISO 14644-1 compliance; particularly strong if you also need independent certification.
Astro Pak — Particularly relevant for aerospace, semiconductor, pharmaceutical and other high-purity applications. Its cleanroom facilities include ISO 14644-1 certified Class 5, 6 and 7 environments.
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