Offers Synthetic Biology Services f… AI recommendations | Parse
Who offers synthetic biology services for custom DNA strand synthesis?
Data as of Sep 26, 2026 · Based on 296 AI responses from ChatGPT Search and Google AI Mode · See how Parse measures this
For high-volume pooled DNA (oligo pools, NGS panels) choose Twist Bioscience for its silicon-based platform. For precise custom oligos, antisense or very long constructs, pick Integrated DNA Technologies (IDT). For end-to-end gene synthesis, sequencing and cloning, use (Azenta).
Best for labs needing high‑accuracy custom oligos, antisense oligos, pools and long or complex constructs (partners enable up to ~50 kb). Caveat: ultra-large builds may be fulfilled via partnerships.
Best when you need large-scale, high-throughput silicon-based synthesis (oligo pools, NGS panels, lots of gene fragments). Tradeoff: optimized for volume and pools rather than bespoke cloning workflows.
Several established providers offer custom DNA synthesis for synthetic-biology research. The right one depends mainly on whether you need short oligos, gene-length dsDNA, cloned genes, or longer constructs.
twistbioscience.com — Gene fragments and sequence-verified clonal genes; particularly geared toward scalable, high-throughput synthesis. Their current standard gene offering goes up to about 5 kb, with separate complex-gene services.
idtdna.com — Custom gene synthesis, dsDNA fragments, and sequence-verified genes delivered in cloning/expression vectors.
.com — Gene synthesis, gene fragments, cloning/subcloning, plasmid preparation, and related molecular-biology services.
synbio-tech.com — Custom gene synthesis including difficult sequences, ssDNA, pathway synthesis, and longer DNA constructs; the company advertises synthesis capabilities extending to ~200 kb for some services.
eurofins.com — DNA/RNA synthesis plus double-stranded, sequence-verified genes and gene fragments.
If by “DNA strand” you mean a relatively short custom oligonucleotide rather than a whole gene, the relevant products are usually called oligo synthesis, while multi-kilobase sequences are generally sold as gene synthesis/gene fragments.
If you tell me the approximate length (e.g., 50 bp, 500 bp, 5 kb, 20 kb+), whether you need single- or double-stranded DNA, and whether it needs to be cloned into a plasmid, I can narrow this to the most relevant providers and compare current pricing/turnaround.
Several established companies and specialized synthetic biology providers offer custom DNA and gene strand synthesis services. They range from high-throughput industrial providers to innovators using novel enzymatic synthesis methods:
Twist Bioscience : Utilizes a proprietary silicon-based high-throughput DNA synthesis platform to manufacture custom synthetic genes, oligo pools, and variant libraries at a large scale.
GenScript : Provides comprehensive custom gene synthesis, DNA/RNA oligo synthesis, codon optimization, and mutagenesis services with rapid turnaround times.
Integrated DNA Technologies (IDT) : Supplies custom gene fragments, standard oligos, clonal genes, and tailored multi-site cloning solutions via automated manufacturing workflows.
Ansa Biotechnologies : Focuses on advanced enzymatic DNA synthesis to produce complex, long-fragment, and difficult-to-obtain clonal DNA sequences.
Synbio Technologies : Offers broad synthetic biology solutions including custom DNA/oligo synthesis, long-fragment assembly, and codon optimization for challenging sequences.
ATUM : Specializes in custom gene design, protein engineering, and synthetic DNA constructs backed by machine learning and optimization algorithms.
DNA Script : Pioneers enzymatic DNA synthesis (EDS) both through direct custom synthesis services (for ssDNA and complex secondary structures) and benchtop printers.
Eurofins Genomics (including Blue Heron) : Delivers custom gene synthesis, complex long DNA constructs, and oligonucleotide modifications for diverse research pipelines.
Telesis Bio : Known for the BioXp system (benchtop automated synthetic biology workstations) and Gibson Assembly methods to build custom DNA, RNA, and proteins on demand.
Ribbon Biolabs : Employs an automated enzymatic platform (InfiniSynth ) geared toward generating long and complex synthetic DNA molecules.
If you can share what length of DNA, sequence complexity , or downstream application (e.g., cloning, mRNA therapeutics, library screening) you are working with, I can help you narrow down which provider fits your project best.
A robust market of synthetic biology companies and commercial providers specialize in custom DNA and gene strand synthesis. They range from high-throughput silicon-platform manufacturers to enzymatic synthesis innovators and traditional global biotech providers.
Prominent providers offering custom DNA strand and gene synthesis services include:
Twist Bioscience Uses a proprietary, high-throughput silicon-based DNA manufacturing platform to manufacture clonal genes, oligo pools, and complex variant libraries rapidly and cost-effectively.
GenScript Biotech One of the largest global providers of de novo gene synthesis, offering fast-turnaround options (like their FLASH Gene service) alongside comprehensive cloning and expression solutions.
Integrated DNA Technologies (IDT) A pioneer in synthetic biology and custom nucleic acids, known for supplying standard and non-standard custom gene fragments (gBlocks), oligonucleotides, and complex gene constructs.
Thermo Fisher Scientific Through its GeneArt platform, provides automated, high-throughput custom gene synthesis, sequence optimization, and diverse gene-to-protein solutions.
Eurofins Genomics Offers custom DNA oligonucleotides and double-stranded gene synthesis via optimized platforms, bolstered by its acquisition of Blue Heron Biotech.
Ansa Biotechnologies Specializes in next-generation enzymatic DNA synthesis (EDS) to produce long, complex, and difficult-to-obtain clonal DNA sequences (up to multi-kb lengths) more cleanly than traditional chemical methods.
Ribbon Biolabs Utilizes an automated, enzyme-based platform (InfiniSynth) geared toward the cost-efficient production of long and complex synthetic DNA molecules without strict sequence or size limitations.
DNA Script Known for next-generation enzymatic DNA synthesis (EDS) services capable of producing customized single-stranded DNA and complex sequence motifs on demand.
ATUM A machine learning-backed synthetic biology tool and CRO provider specializing in robust gene design, custom gene synthesis, and protein engineering.
If you can share what length of DNA, complexity , and turnaround time you need, I can help narrow down which provider best fits your project specifications.
twistbioscience.com — gene fragments and clonal genes, including complex constructs.
idtdna.com — custom dsDNA fragments and sequence-verified genes.
genscript.com — gene synthesis and long DNA constructs, including GenBrick services.
eurofins.com — gene fragments through complex gene constructs.
For choosing among them, the key variables are sequence length/complexity, linear DNA vs. plasmid, turnaround time, quantity, QC requirements, and price.
A wide range of biotechnology and synthetic biology companies specialize in custom DNA and gene strand synthesis, ranging from high-throughput silicon-based providers to global contract research organizations.
Twist Bioscience utilizes a proprietary silicon-based high-throughput platform to manufacture custom oligonucleotides, gene fragments, and clonal genes economically and at scale.
GenScript is a major global provider offering comprehensive custom gene synthesis, molecular biology services, and sequence optimization tools.
Integrated DNA Technologies (IDT) is an industry staple widely used for custom DNA oligonucleotides, gene fragments, and complex clonal genes.
ATUM provides custom gene design, protein engineering, and synthetic biology solutions backed by machine learning tools.
Eurofins Genomics delivers comprehensive genomic services, custom DNA oligos, and full-scale gene synthesis worldwide.
DNA Script pioneers enzymatic DNA synthesis (EDS) to provide custom single-stranded DNA (ssDNA) oligonucleotides both via direct synthesis services and benchtop instruments.
Camena Bioscience specializes in multi-enzymatic DNA and synthetic biology applications designed to deliver high-accuracy custom strands.
If you have a specific project in mind, tell me:
What length and type of DNA strand (oligo, fragment, or clonal gene) you need
Your target turnaround time or scale
I can help you narrow down which provider matches your exact requirements.
Yes. Several established synthetic-biology companies offer custom DNA synthesis, ranging from short oligos to full synthetic genes and larger constructs:
Integrated DNA Technologies (IDT) — Custom single-stranded DNA oligos, pooled oligos, gene fragments, and sequence-verified synthetic genes. Their standard gene-synthesis offering covers roughly 25 bp to >5 kb.
Twist Bioscience — Gene fragments, clonal genes, pooled genes, and complex gene synthesis; particularly geared toward synthetic biology and high-throughput applications.
GenScript — Custom DNA oligos up to 218 nt, plus gene synthesis and larger DNA constructs. Its GenBrick service supports much larger synthetic DNA assemblies.
Thermo Fisher Scientific — Custom DNA oligonucleotides in tubes and plates, including large-scale synthesis and modified oligos.
Eurofins Genomics — Custom DNA/RNA synthesis, gene fragments, genes, sequencing, and related genomic services.
Eton Bioscience — Custom DNA/RNA oligos from approximately 5–200 bases, with extensive modification options and scales from micrograms to kilograms.
Which type should you use?
Short DNA strands / primers (≈20–200 bases): IDT, GenScript, Thermo Fisher, Eton, or Eurofins.
Longer double-stranded fragments / genes: IDT, Twist, GenScript, or Eurofins.
Large synthetic-biology constructs: GenScript and Twist are particularly worth comparing.
Modified DNA (fluorophores, linkers, unusual bases, etc.): IDT and GenScript have extensive modification catalogs.
If you tell me the approximate strand length, whether you need single- or double-stranded DNA, quantity, and any modifications, I can narrow this to the best 2–3 providers and compare price, turnaround, sequence-length limits, and QC.
Several prominent synthetic biology companies and biotechnology providers specialize in custom DNA strand and gene synthesis. They utilize diverse platforms—ranging from traditional high-throughput chemical synthesis to silicon-based and enzymatic approaches.
Twist Bioscience utilizes a proprietary silicon-based, high-throughput platform to manufacture customized clonal genes, gene fragments, and oligonucleotide libraries with high sequence accuracy and scalability.
Integrated DNA Technologies (IDT) provides comprehensive custom gene synthesis, standard/complex double-stranded DNA constructs, and gene fragments, alongside collaborative enzymatic options through partnerships (such as Ansa Biotechnologies) for challenging sequences.
GenScript Biotech Corporation is one of the world's largest commercial gene synthesis providers, offering custom gene construction, codon optimization, cloning, and rapid turnaround options.
DNA Script specializes in proprietary Enzymatic DNA Synthesis (EDS) technology, enabling custom single-stranded DNA (ssDNA) and oligos without relying strictly on traditional petroleum-based chemical methods.
ATUM offers integrated synthetic biology services, including gene design, custom gene synthesis, protein engineering, and optimization algorithms via platforms like GeneGPS.
If you're looking for a specific type of service, let me know:
Are you aiming for standard oligonucleotides, clonal genes , or large gene fragments/pathways?
Do you have a preferred turnaround time or budget scale?
I can help narrow down which provider best fits your project parameters.
Several major synthetic-biology providers offer custom DNA synthesis, ranging from short oligos and gene fragments to complete cloned genes and large DNA constructs:
Integrated DNA Technologies (IDT) — Custom single- and double-stranded DNA, gBlocks gene fragments, and sequence-verified gene synthesis. Their current gene-synthesis range starts around 25 bp and extends beyond 5 kb, with more complex constructs available through their Ansa workflow.
Twist Bioscience — Gene fragments and NGS-verified clonal genes, including synthesis in a customer-supplied vector. Twist lists gene fragments from roughly 0.3–5 kb and accelerated synthesis options.
GenScript — Gene synthesis and larger synthetic-DNA constructs; its GenBrick service advertises constructs up to 200 kb.
Eurofins Genomics — Custom oligos, linear dsDNA gene fragments, sequence-verified genes, and complex gene constructs. Its GeneStrands fragments are available up to 3,000 bp.
Which one to choose?
Need
Good starting options
Short custom DNA/oligos
IDT, Eurofins
~0.1–3 kb DNA fragments
IDT, Twist, Eurofins
Complete synthetic genes in plasmids
IDT, Twist, GenScript
Complex/long DNA constructs
GenScript, IDT/Ansa
Fast turnaround
If you tell me the approximate strand length (e.g., 100 bp, 2 kb, 20 kb), whether you need single- or double-stranded DNA, and whether you need it cloned into a plasmid, I can narrow this down to the 2–3 best suppliers and compare current pricing/turnaround.
Several leading synthetic biology companies provide custom DNA strand synthesis, ranging from short oligonucleotide fragments to ultra-long, complex genes.
The premier service providers are categorized below by their technological specialties:
High-Throughput & Silicon-Based Synthesis
Twist Bioscience : A dominant leader utilizing a proprietary silicon semiconductor platform. They specialize in high-throughput, highly customizable clonal genes and gene fragments at a low cost-per-base.
GenScript : One of the largest global providers. They offer high-capacity synthesis, complex construct assembly, plasmid preparation, and a 99.95% success rate.[2]
Standard Gene & Fragment Synthesis Providers
Integrated DNA Technologies (IDT) : Known for their industry-standard gBlocks and gBlocks HiFi Gene Fragments. They are excellent for both single-stranded and double-stranded custom DNA.
Thermo Fisher Scientific (GeneArt) : Their GeneArt portfolio handles large and complex genes. They feature the GeneOptimizer algorithm for advanced codon optimization.
Next-Gen Enzymatic & Long DNA Specialists
Ansa Biotechnologies : Uses an innovative enzyme-based platform rather than traditional chemical printing. This allows direct synthesis of complex sequences up to 900 base pairs and seamless clonal assemblies up to 50 kb.
Ribbon Biolabs : Focuses on the fast synthesis of exceptionally long DNA molecules (ranging from 5,000 to 50,000 base pairs) for biopharma applications.
: Rather than outsourcing, they offer the , an enzymatic benchtop DNA "printer" allowing you to synthesize custom oligos directly in your own lab.
To recommend the best vendor, could you tell me a little more about your target construct?
What is the approximate length of the strand (e.g., oligos, 1-2 kb fragments, or >5 kb constructs)?
Does the sequence contain complex elements like high GC-content or heavy repeats?
Yes. Several established providers offer custom DNA synthesis / gene synthesis for synthetic-biology workflows:
idtdna.com — Custom DNA oligos, linear gene fragments, and sequence-verified clonal genes. Their current gene-synthesis range starts around 25 bp and extends beyond 5 kb, with higher-complexity constructs available through custom projects.
twistbioscience.com — Gene fragments and NGS-verified clonal genes, including custom vectors and accelerated synthesis options. Their standard gene offering covers roughly 0.3–5 kb.
eurofins.com — Custom DNA/RNA synthesis plus sequence-verified genes and gene fragments, ranging from relatively simple fragments to complex constructs.
GenScript — A major provider of custom gene synthesis, DNA fragments, and broader synthetic-biology services.
Thermo Fisher Scientific / GeneArt — Custom gene synthesis and DNA constructs, particularly useful if you also need cloning, expression, or other molecular-biology services.
Which one should you choose?
For a straightforward custom DNA strand/fragment, I'd compare IDT, Twist, and Eurofins on price, length, turnaround, sequence complexity, and whether you need linear DNA versus a cloned plasmid. For a larger synthetic-biology project, providers that offer gene synthesis + cloning + sequence verification can save substantial time.
If you tell me the approximate DNA length (e.g. 100 bp, 1 kb, 10 kb), whether you need ssDNA or dsDNA, and your desired quantity, I can compare the best providers and current pricing/turnaround.
