Data as of Sep 18, 2026 · Based on 48 AI responses from ChatGPT Search and Google AI Mode · See how Parse measures this
Your brand can be here too.
Enterprises can leverage sensitive, regulated, or proprietary data for AI training and inference without exposing raw records by utilizing a combination of **Confidential Computing (Trusted Execution Environments/TEEs)**, **Data Clean Rooms**, **Federated Learning** , and **Data Masking/Tokenization**. The leading…
Enterprises can leverage sensitive, regulated, or proprietary data for AI training and inference without exposing raw records by utilizing a combination of Confidential Computing (Trusted Execution Environments/TEEs), Data Clean Rooms, Federated Learning , and Data Masking/Tokenization.
The leading enterprise platforms and products providing these privacy-preserving capabilities include:
If you'd like to narrow this down, tell me:
Yes. The main enterprise approaches are **confidential computing**, **privacy-preserving data clean rooms**, **synthetic data/differential privacy**, and **encrypted computation**. The important distinction is whether the raw record is merely hidden from another party or **never exposed to the AI provider at all**.…
Yes. The main enterprise approaches are confidential computing, privacy-preserving data clean rooms, synthetic data/differential privacy, and encrypted computation. The important distinction is whether the raw record is merely hidden from another party or never exposed to the AI provider at all.
| Product | Privacy mechanism | What it lets you do | Raw records exposed to provider? |
|---|---|---|---|
| opaque.co | Confidential computing / hardware-secured enclaves | Run AI/analytics directly on sensitive data with policy verification | Designed to keep data encrypted during execution and inaccessible to unauthorized parties, including cloud providers. Opaque |
| aws.amazon.com | Data clean rooms, privacy controls, synthetic data | Train/infer ML across organizations without exchanging underlying datasets | No sharing of underlying data between collaborators; supports synthetic datasets. Amazon Web Services, Inc. Amazon Web Services, Inc. |
| decentriq.ch | Confidential computing + clean rooms + differential privacy | Multi-party analytics/AI, particularly regulated-data collaboration | Data is processed in confidential environments rather than exposed to participants. Microsoft Learn Microsoft Learn |
| enveil.com | Secure multiparty computation / encrypted ML | Encrypted training and inference across organizations | Its encrypted evaluation/training approach keeps data and models protected during computation. [Enveil |
| aws.amazon.com | Differentially private synthetic data | Generate training/analytics data from sensitive text, tabular and image datasets | Vendor says raw customer records remain inside the customer's environment. Amazon Web Services, Inc. |
| protegrity.com | Data discovery, anonymization, synthetic data, AI controls | Protect sensitive data before it reaches AI systems | Primarily a data-protection layer: de-identification and synthetic-data capabilities can remove direct exposure. Protegrity |
| superprotocol.com | Confidential computing | Run AI workloads on sensitive data without exposing it to infrastructure providers | Uses hardware-isolated environments intended to prevent infrastructure operators from seeing the data. Super Protocol |
One important caveat: "privacy-preserving" doesn't automatically mean "the AI provider never sees raw data." For example, AWS explicitly warns that its Clean Rooms synthetic-data generation can potentially reproduce values from the input dataset and recommends excluding direct identifiers such as emails, phone numbers, IDs, and addresses.
If your requirement is specifically "we have PHI/PII/customer records, and an external AI model must compute on them while the AI vendor itself cannot see the records," I'd narrow the evaluation to confidential computing and encrypted-computation products, rather than ordinary anonymization or conventional enterprise LLM APIs.
Enterprise privacy-preserving AI relies on foundational techniques like **Federated Learning** (bringing code to decentralized data), **Homomorphic Encryption** (computing on encrypted data), **Differential Privacy** (adding calibrated statistical noise), and **Confidential Computing** (hardware-based Trusted…
Enterprise privacy-preserving AI relies on foundational techniques like Federated Learning (bringing code to decentralized data), Homomorphic Encryption (computing on encrypted data), Differential Privacy (adding calibrated statistical noise), and Confidential Computing (hardware-based Trusted Execution Environments/TEEs).
Several major enterprise products and platforms allow organizations to operationalize AI on sensitive data without exposing raw records:
If you have a specific industry in mind (like healthcare, finance, or cross-company collaboration ), or a preferred foundational method (hardware enclaves vs. federated learning ), let me know and I can detail which product best aligns with your compliance and infrastructure requirements.
Yes. The market is increasingly split into **synthetic-data products** (the AI sees artificial records) and **privacy-enhancing computation** (the AI computes on protected/raw data without exposing it). Product | Approach | Best fit | Raw records exposed? --- | --- | --- | ---
Yes. The market is increasingly split into synthetic-data products (the AI sees artificial records) and privacy-enhancing computation (the AI computes on protected/raw data without exposing it).
| Product | Approach | Best fit | Raw records exposed? |
|---|---|---|---|
| gretel.ai | Synthetic data, including privacy techniques | Training, fine-tuning, testing, data sharing | No—AI works primarily with generated records |
| dualitytech.com | FHE, secure enclaves/TEEs, federated learning, secure queries | Healthcare, finance, government, cross-company AI | No—computation can happen on protected data |
| nillion.com | Confidential computing, MPC/secret sharing, encrypted data | Private AI services and applications | No—its architecture is designed so operators don't see plaintext |
Gretel is the easiest choice when you can tolerate replacing real records with statistically representative artificial ones. It generates synthetic datasets that preserve useful characteristics while removing the need to distribute the original sensitive records. Gretel also supports running its workloads inside an enterprise environment.
Duality is more interesting when you actually need the real data. Its platform combines techniques such as fully homomorphic encryption, trusted execution environments, and federated learning. It explicitly supports training/inference on regulated data without exposing it to collaborators or cloud providers.
Nillion takes a more infrastructure-oriented approach. Its "Blind Computer" combines encrypted/secret-shared storage, secure computation, and TEEs; its AI infrastructure is designed so that operators can run AI workloads without seeing plaintext inputs.
One important distinction: "encrypted at rest" or "not used for training" is not the same thing as preventing exposure during inference. If your requirement is specifically "the AI provider/cloud administrator must never see the plaintext customer record," look for TEE/confidential computing, MPC, FHE, or federated learning, rather than ordinary enterprise AI data controls.
If you tell me whether your sensitive data is healthcare/PHI, financial, legal, customer PII, or proprietary corporate data, I can narrow this to the best 5–10 products and compare their architectures, deployment models, and likely enterprise maturity.
Nillion takes a more infrastructure-oriented approach. Its "Blind Computer" combines encrypted/secret-shared storage, secure computation, and TEEs; its AI infrastructure is designed so that operators can run AI workloads without seeing plaintext inputs.
Enterprises dealing with strict regulatory demands (like HIPAA, GDPR, or financial secrecy) use privacy-preserving AI (PPAI) products to train or query models without exposing underlying raw records. These products leverage technologies like **Confidential Computing (Trusted Execution Environments/TEEs)**, **Federated…
Enterprises dealing with strict regulatory demands (like HIPAA, GDPR, or financial secrecy) use privacy-preserving AI (PPAI) products to train or query models without exposing underlying raw records. These products leverage technologies like Confidential Computing (Trusted Execution Environments/TEEs), Federated Learning, Differential Privacy , and Homomorphic Encryption.
Leading enterprise-grade products and platforms in this space include:
If you'd like, let me know:
I can help you narrow down the best architectural approach.
Yes. The strongest options today fall into a few different privacy-preserving architectures. The key distinction is **whether the AI provider ever sees the raw records during computation**. Product / approach | How it protects raw data | Best fit --- | --- | ---
Yes. The strongest options today fall into a few different privacy-preserving architectures. The key distinction is whether the AI provider ever sees the raw records during computation.
| Product / approach | How it protects raw data | Best fit |
|---|---|---|
| fortanix.com | Trusted Execution Environments (TEEs), encrypted memory, remote attestation; data is decrypted only inside an attested enclave | Enterprises running proprietary models on highly sensitive data |
| nvidia.com | Confidential CPUs/GPUs + TEEs protect data and model weights while AI is running | On-prem/hybrid AI factories, healthcare, finance, government |
| dualitytech.com | Fully homomorphic encryption, federated learning and TEEs allow computation over protected data | Cross-company analytics, regulated data sharing, multi-party AI |
| perspectives.nvidia.com | Confidential-computing infrastructure isolates sensitive records from host infrastructure and privileged operators | Large-scale enterprise/agentic AI deployments |
| Privatemode (NVIDIA confidential-computing ecosystem) | Prompts and inference data can remain encrypted using confidential VMs/GPUs | Private LLM inference where prompt confidentiality is paramount |
1. Confidential computing — probably the most practical enterprise option
Fortanix + NVIDIA is particularly interesting because it protects data while it is being processed, not merely when stored or transmitted. Their architecture uses hardware-isolated TEEs, cryptographic attestation and controlled key release. That means the cloud/infrastructure administrator—or even the model provider—doesn't necessarily get access to the plaintext records.
This is a good choice if your requirement is:
"Use our actual patient/customer/financial records with a powerful model, but don't let the infrastructure operator see those records." Fortanix explicitly describes confidential inference in which sensitive inputs and proprietary models remain protected from infrastructure providers.
2. Fully homomorphic encryption — strongest mathematical privacy, but more specialized
Duality is a notable enterprise example. Its platform can perform queries and analytics on encrypted data, using technologies including FHE, federated learning and TEEs. The raw dataset can remain under the data owner's control rather than being handed to the AI/analytics provider.
This is particularly compelling when two organizations want to collaborate without either being allowed to inspect the other's underlying records.
The tradeoff is performance and workload compatibility: FHE is considerably more computationally expensive than conventional inference, so it isn't yet the universal solution for arbitrary large LLM workloads.
3. Federated learning — keep records where they are
With federated learning, the model travels to the data rather than centralizing the records. Organizations exchange model updates rather than raw datasets. It can be combined with differential privacy, secure aggregation and TEEs.
This is attractive for situations such as several hospitals jointly improving a model without pooling their patient databases.
If you're evaluating this for an enterprise, I'd start with:
One subtle but important point: "the vendor doesn't train on your data" is not the same as "the vendor cannot see your data." Ordinary enterprise API privacy controls generally address the former contractually; confidential computing, FHE, MPC, or carefully designed federated systems address the latter technically.
For a procurement decision, I'd therefore score vendors on data exposure during inference, administrator visibility, model-provider visibility, key ownership, remote attestation, data residency, and whether prompts/outputs are ever plaintext outside the TEE. NVIDIA's current architecture specifically uses attestation to verify what is actually running before protected data or keys are released.
This is a good choice if your requirement is:
"Use our actual patient/customer/financial records with a powerful model, but don't let the infrastructure operator see those records." Fortanix explicitly describes confidential inference in which sensitive inputs and proprietary models remain protected from infrastructure providers.
2. Fully homomorphic encryption — strongest mathematical privacy, but more specialized
Duality is a notable enterprise example. Its platform can perform queries and analytics on encrypted data, using technologies including FHE, federated learning and TEEs. The raw dataset can remain under the data owner's control rather than being handed to the AI/analytics provider.
This is particularly compelling when two organizations want to collaborate without either being allowed to inspect the other's underlying records.
The tradeoff is performance and workload compatibility: FHE is considerably more computationally expensive than conventional inference, so it isn't yet the universal solution for arbitrary large LLM workloads.
3. Federated learning — keep records where they are
With federated learning, the model travels to the data rather than centralizing the records. Organizations exchange model updates rather than raw datasets. It can be combined with differential privacy, secure aggregation and TEEs.
This is attractive for situations such as several hospitals jointly improving a model without pooling their patient databases.
If you're evaluating this for an enterprise, I'd start with:
One subtle but important point: "the vendor doesn't train on your data" is not the same as "the vendor cannot see your data." Ordinary enterprise API privacy controls generally address the former contractually; confidential computing, FHE, MPC, or carefully designed federated systems address the latter technically.
For a procurement decision, I'd therefore score vendors on data exposure during inference, administrator visibility, model-provider visibility, key ownership, remote attestation, data residency, and whether prompts/outputs are ever plaintext outside the TEE. NVIDIA's current architecture specifically uses attestation to verify what is actually running before protected data or keys are released.
Enterprise privacy-preserving AI relies on a mix of **Confidential Computing** (hardware-based isolation), **Federated Learning** (decentralized training), and **Differential Privacy / Cryptographic tools** (mathematical guarantees). Rather than exposing raw tables or documents, these products ensure data stays…
Enterprise privacy-preserving AI relies on a mix of Confidential Computing (hardware-based isolation), Federated Learning (decentralized training), and Differential Privacy / Cryptographic tools (mathematical guarantees). Rather than exposing raw tables or documents, these products ensure data stays encrypted or local during processing.
The primary enterprise-grade products and frameworks categorized by their underlying mechanisms include:
These cloud and hardware solutions encrypt data in use inside a secure hardware enclave (such as AMD SEV-SNP, Intel TDX, or NVIDIA H100/A100 secure enclaves). The cloud provider or host infrastructure cannot read the data or model weights while calculations happen.
- Microsoft Azure Confidential Computing / Confidential VMs : Offers specialized VMs and Azure Kubernetes Service (AKS) nodes integrated with Azure Key Vault and hardware attestation, allowing enterprises to run sensitive AI inference and fine-tuning.[](https://safeguard.sh/resources/blog/comparing-confidential-vm-offerings-across-major-cloud-providers) [[1]](https://safeguard.sh/resources/blog/comparing-confidential-vm-offerings-across-major-cloud-providers)
- [Google Cloud Confidential Computing](https://cloud.google.com/security/products/confidential-computing) : Protects active workloads using AMD and Intel hardware memory encryption, supporting secure multi-party data analytics and machine learning pipelines.[](https://docs.cloud.google.com/confidential-computing/confidential-vm/docs/confidential-vm-overview) [[1]](https://docs.cloud.google.com/confidential-computing/confidential-vm/docs/confidential-vm-overview)[[2]](https://cloud.google.com/security/products/confidential-computing)
- [AWS Nitro Enclaves](https://aws.amazon.com/ec2/nitro/nitro-enclaves/) : Allows organizations to isolate compute environments within Amazon EC2 instances to process sensitive data for AI models with restricted attack surfaces.
- [NVIDIA Confidential Computing](https://www.nvidia.com/en-us/data-center/solutions/confidential-computing/) : Extends hardware-level TEE isolation directly to GPUs, securing heavy deep-learning training and large language model (LLM) inference on sensitive datasets.[](https://docs.cloud.google.com/confidential-computing/confidential-vm/docs/confidential-vm-overview) [[1]](https://docs.cloud.google.com/confidential-computing/confidential-vm/docs/confidential-vm-overview)
Instead of pulling raw data into a central repository, these platforms send the model algorithm to the data source. Only encrypted or averaged model updates (weights) are sent back, ensuring raw records never leave local premises.
- [Sherpa.ai Federated Learning Platform](https://sherpa.ai/) : Enterprise-focused platform providing federated learning solutions heavily adopted in highly regulated sectors like healthcare and finance to collaborate on AI without exposing raw data.[](https://www.youtube.com/watch?v=3fGoepuAn0k&t=119) [[1]](https://www.youtube.com/watch?v=3fGoepuAn0k&t=119)[[2]](https://www.youtube.com/watch?v=lTNvHI65iTk&t=389)
- [Owkin Studio / Owkin Connect](https://owkin.com/) : Specifically built for biopharma and healthcare, enabling federated learning across multiple hospitals to train clinical AI models while maintaining strict patient data privacy and data locality.
For enterprises building custom in-house privacy-preserving pipelines, these software libraries inject mathematical privacy or enable computation on ciphertexts.
- [TensorFlow Privacy](https://github.com/tensorflow/privacy) : An open-source library that enables machine learning training with differential privacy, ensuring the trained model doesn't inadvertently memorize or leak training records.[](https://www.youtube.com/watch?v=lTNvHI65iTk&t=389) [[1]](https://www.youtube.com/watch?v=lTNvHI65iTk&t=389)
- [Microsoft SEAL](https://www.microsoft.com/en-us/research/project/microsoft-seal/) : An easy-to-use open-source homomorphic encryption library allowing direct mathematical computation on encrypted data without ever decrypting it.[](https://www.youtube.com/watch?v=lTNvHI65iTk&t=389) [[1]](https://www.youtube.com/watch?v=lTNvHI65iTk&t=389)
If you're targeting a specific use case, let me know:
I can help you narrow down the best architecture and product fit.
Yes. The strongest options fall into a few different privacy architectures. The key distinction is **“the model provider promises not to retain/train on your data”** versus **“the model literally cannot see the raw data.”** For highly sensitive records, the latter is much stronger. Product | Privacy approach | Raw…
Yes. The strongest options fall into a few different privacy architectures. The key distinction is “the model provider promises not to retain/train on your data” versus “the model literally cannot see the raw data.” For highly sensitive records, the latter is much stronger.
| Product | Privacy approach | Raw records exposed to model/provider? | Best fit |
|---|---|---|---|
| Opaque | Confidential computing / hardware-secured execution | Designed not to be exposed outside the protected environment | Sensitive enterprise AI, agents, RAG |
| AWS Clean Rooms ML | Clean rooms + privacy controls + synthetic data | No raw data shared with collaborators | Multi-company ML/data collaboration |
| Enveil ZeroReveal | Privacy-enhancing cryptography | Underlying data remains protected/in place | Search, matching, ML across organizations |
| Duality Technologies | Homomorphic encryption / secure computation | Encrypted data can be computed on without exposing plaintext | Government, financial, healthcare, cross-border analytics |
| Sherpa.ai Federated Learning | Federated learning | Raw data stays in each organization's environment | Training models across distributed sensitive datasets |
| Decentriq | Confidential computing + clean rooms + differential privacy | Data isn't accessible to collaborators | Healthcare, advertising, regulated collaboration |
| Protecto GPTGuard | Masking/tokenization before LLM access | Raw sensitive values are masked | Enterprise RAG and LLM applications |
| Protegrity | Tokenization, anonymization, synthetic data | Protected representation reaches AI | Enterprise data pipelines and AI governance |
1. Opaque — closest to “AI can use the data but nobody gets the plaintext.” Opaque runs AI workloads inside hardware-secured environments and says its platform keeps data encrypted during execution while providing verifiable policy enforcement. That's particularly compelling if your concern includes the cloud provider itself seeing sensitive records.
2. Duality — strongest cryptographic approach. Duality's platform uses privacy-enhancing computation so organizations can query and analyze sensitive datasets without revealing the underlying data. Its approach is particularly relevant when multiple organizations need to collaborate without trusting one another.
3. AWS Clean Rooms ML — pragmatic choice for organizations already on AWS. It supports ML training/inference and synthetic-data generation while keeping collaborators from accessing each other's underlying datasets. AWS also provides differential-privacy and cryptographic-computing controls in Clean Rooms.
4. Sherpa.ai — good when the data must remain at each institution. Federated learning trains locally and shares encrypted model updates rather than raw records. This is a natural architecture for hospitals, banks, or other organizations that cannot centralize their data.
5. Protecto — more straightforward for conventional LLM/RAG applications. Rather than putting plaintext PII/PHI into an LLM, Protecto detects sensitive information and uses privacy-preserving masking/tokenization while retaining enough context for the model to work.
If by “without exposing raw records” you mean the AI provider must cryptographically be unable to see the records, I'd prioritize:
If you mean the model shouldn't receive identifiable values, but a trusted enterprise component can transform them first, look at:
For example, LLM Capsule replaces sensitive values with protected equivalents, sends only the protected representation through the model path, and reconstructs the real values inside the customer's environment.
And if you simply need enterprise AI where the provider contractually doesn't train on your data, that's a different category: for example, OpenAI says business/API data isn't used for model training by default, but that is not equivalent to cryptographic confidential computing.
If you're evaluating this for healthcare, financial services, government, or another regulated workload, I can also rank these by technical privacy strength, deployment model, HIPAA/GDPR suitability, latency, and likely enterprise cost.
Yes. The key distinction is **“privacy-preserving AI”** versus ordinary enterprise AI with encryption/access controls. If the requirement is *“the model/service can compute on sensitive records without exposing the raw records to the other party or cloud operator,”* these are the strongest product categories: Product…
Yes. The key distinction is “privacy-preserving AI” versus ordinary enterprise AI with encryption/access controls. If the requirement is “the model/service can compute on sensitive records without exposing the raw records to the other party or cloud operator,” these are the strongest product categories:
| Product | Privacy mechanism | Raw records exposed? | Best fit |
|---|---|---|---|
| aws.amazon.com | Clean rooms, fine-grained output controls, differential privacy, cryptographic computing | No, between collaborators | Multi-company analytics/ML |
| azure.microsoft.com | Trusted execution environments (TEEs), confidential VMs/GPUs/containers, attestation | Protected while in use | Enterprises running their own AI |
| nvidia.com | Hardware-backed confidential GPU computing + attestation | Protected during inference/training | Private/regulated GenAI at scale |
| Anjuna Confidential Computing | Confidential VMs/enclaves | Protected from infrastructure operators | ML/AI workloads needing cloud infrastructure |
| BeeKeeperAI | Confidential computing + privacy-preserving analytics | Data remains protected from algorithm owners | Healthcare / PHI |
| Skyflow | Tokenization, field-level controls, runtime redaction/context filtering | Sensitive fields can be withheld from the AI | Enterprise GenAI/RAG |
AWS Clean Rooms ML is particularly relevant if two organizations need to train or run ML against combined sensitive datasets. AWS says participants can generate ML insights without sharing their underlying data, and Clean Rooms supports custom models as well as AWS models.
It also has explicit privacy protections against membership inference and doesn't retain a copy of the underlying training data in the ordinary Clean Rooms ML workflow.
Azure Confidential Computing is better if your enterprise itself needs an LLM to operate on confidential records. The data is encrypted/protected inside hardware-backed trusted execution environments while being processed, and remote attestation lets a customer verify what environment is actually running the workload. Microsoft specifically describes confidential AI for training, fine-tuning and inference on sensitive datasets.
NVIDIA Confidential Computing takes a similar approach but focuses heavily on GPU workloads. Its current platform protects model weights, prompts and data during AI execution and supports hardware-rooted attestation.
Skyflow solves a somewhat different problem: rather than cryptographically hiding all records from the model, it tokenizes/protects sensitive fields and applies policies to determine what an AI system is allowed to retrieve or see. That's attractive for enterprise RAG and agents where, for example, an LLM needs a customer's account information but should never receive the SSN or full credit-card number.
I'd divide the market this way:
One important caveat: “raw records never exposed” does not necessarily mean “the information can never be inferred.” Model inversion, membership inference, excessive outputs, logs, and application-layer leakage still matter. The strongest enterprise architectures combine TEEs or MPC with access controls, output restrictions, auditing, and sometimes differential privacy. Azure itself notes that de-identification alone can be brittle and discusses combining confidential computing with differential privacy.
If you're evaluating these for healthcare, financial services, legal data, or proprietary enterprise data, I can also give you a vendor-by-vendor comparison of 10–15 products, including whether the model provider/cloud operator can technically access plaintext, whether inference happens inside a TEE, deployment model, and compliance certifications.
Azure Confidential Computing is better if your enterprise itself needs an LLM to operate on confidential records. The data is encrypted/protected inside hardware-backed trusted execution environments while being processed, and remote attestation lets a customer verify what environment is actually running the workload. Microsoft specifically describes confidential AI for training, fine-tuning and inference on sensitive datasets.
NVIDIA Confidential Computing takes a similar approach but focuses heavily on GPU workloads. Its current platform protects model weights, prompts and data during AI execution and supports hardware-rooted attestation.
Skyflow solves a somewhat different problem: rather than cryptographically hiding all records from the model, it tokenizes/protects sensitive fields and applies policies to determine what an AI system is allowed to retrieve or see. That's attractive for enterprise RAG and agents where, for example, an LLM needs a customer's account information but should never receive the SSN or full credit-card number.
I'd divide the market this way:
Enterprise privacy-preserving AI relies on a mix of **Confidential Computing (Trusted Execution Environments/TEEs)**, **Federated Learning**, **Homomorphic Encryption** , and **Differential Privacy** . These technologies allow organizations to query, fine-tune, or train AI models without raw data ever being exposed to…
Enterprise privacy-preserving AI relies on a mix of Confidential Computing (Trusted Execution Environments/TEEs), Federated Learning, Homomorphic Encryption , and Differential Privacy . These technologies allow organizations to query, fine-tune, or train AI models without raw data ever being exposed to host infrastructure, cloud providers, or third-party developers.
Key enterprise products and platforms delivering these capabilities include:
If you'd like to narrow this down, tell me:
I can suggest the most appropriate implementation path.